If you are struggling with a fentanyl addiction, also known as an opioid use disorder, you may find that it’s challenging to stop using fentanyl on your own. 6 It’s important to know the signs of fentanyl addiction so you can get help for yourself or someone else. Fentanyl addiction is characterized by compulsive fentanyl use despite negative consequences you may experience. This pattern of abstinence and return to use can ultimately create a cycle of problematic fentanyl use that can be difficult to stop. Taking fentanyl will then alleviate these withdrawal symptoms. If you are dependent and you abruptly quit using fentanyl, you will experience unpleasant and distressing withdrawal symptoms. Bacterial endocarditis (infection of the heart lining)Īlthough not synonymous with addiction, dependence can contribute to the development of addiction.Peripheral edema (swelling of legs or hands).People who inject fentanyl may be at risk for additional long-term consequences, such as: 6 Tolerance, or requiring more fentanyl to experience the desired effects.Physiological dependence, meaning you’ll experience fentanyl withdrawal symptoms when you suddenly quit.